HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-5-methyloctahydropyrrolo[3,4-b]pyrrole → 5-Methyl-octahydropyrrolo(3,4-b)pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-5-methyloctahydropyrrolo[3,4-b]pyrrole | HCID 19100962 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Methyl-octahydropyrrolo(3,4-b)pyrrole | HCID 16228899 | — |
Reaction Steps
10.3 g (47.6 mmol) of 2-benzyl-7-methyl-2,7-diazabicyclo(3.3.0]octane in 200 ml of ethanol are hydrogenated on 2.5 g of palladium/active carbon (10% Pd) at 100° C. and 100 bar. The catalyst is filtered off with suction, the filtrate is concentrated, and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05284855 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-5f5dbde6bc2445e8ba8c306010fc8159 |
| Source note | uspto-grants-1994_02 |