Cuminaldehyde → HCID 135930676, compound

HRID 1975243Notes

Reaction equation

HRID 1975243 reaction equation
[CH:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[NH:12]1[CH:16]=[CH:15][CH:14]=[CH:13]1>C(O)(=O)CC>[CH:1]([C:4]1[CH:11]=[CH:10][C:7]([C:8]2[C:16]3[NH:12][C:13]([C:8]([C:7]4[CH:10]=[CH:11][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=4)=[C:13]4[N:12]=[C:16]([C:8]([C:7]5[CH:10]=[CH:11][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=5)=[C:13]5[NH:12][C:16](=[C:8]([C:7]6[CH:6]=[CH:5][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:11][CH:10]=6)[C:13]6[CH:14]=[CH:15][C:16]=2[N:12]=6)[CH:15]=[CH:14]5)[CH:15]=[CH:14]4)=[CH:14][CH:15]=3)=[CH:6][CH:5]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 326CuminaldehydeHCID 8027Pyrrole

Product 1

HCID 135930676HCID 135930676, compound

Reagents, catalysts & solvents 1

HCID 1032Propionic AcidSolvent

Procedure

Under the conditions of example 4a, 14.82 g (100 mmol) of 4-isopropylbenzaldehyde is reacted with 6.92 ml (100 mmol) of pyrrole in 300 ml of propionic acid. The solution is evaporated to dryness in a vacuum. The residue is heated with 200 ml of ethanol quickly to boiling. It is left to cool slowly, the title compound is suctioned off, washed with a little ethanol and dried at 50° C. in a vacuum.

Workup

  1. customThe solution is evaporated to dryness in a vacuum
  2. temperatureThe residue is heated with 200 ml of ethanol quickly
  3. waitIt is left
  4. temperatureto cool slowly
  5. washwashed with a little ethanol
  6. customdried at 50° C. in a vacuum

Sources & evidence

ORD record
ord-1b1c1010967749beac23acec990dd4a3
Source dataset
uspto-grants-1994_02
Patent number
US05284647

Reaction notes

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