Sulfuric Acid → HCID 10656042, compound

HRID 1975322Notes

Reaction equation

HRID 1975322 reaction equation
S(=O)(=O)(O)O.[F:6][C:7]1[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:8]=1[CH2:9][C:10]1(C(OC)=O)[CH2:14][CH2:13][CH2:12][C:11]1=[O:15]>C(O)(=O)C>[F:6][C:7]1[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:8]=1[CH2:9][CH:10]1[CH2:14][CH2:13][CH2:12][C:11]1=[O:15]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 10516025HCID 10516025, compound

Product 1

HCID 10656042HCID 10656042, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a stirred solution of glacial acetic acid (100 ml) and an aqueous solution of sulfuric acid (12.5%, 30 ml), there was added methyl 1-(2,4-difluorobenzyl)-2-oxocyclopentanecarboxylate (5.14 g, 21.6 mmol). The mixture was refluxed in a stream of argon for 5 h.

Workup

  1. temperatureThe mixture was refluxed in a stream of argon for 5 h.

Sources & evidence

ORD record
ord-3e47b7460aa94e8985812e0ba23aa96c
Source dataset
uspto-grants-1994_02
Patent number
US05286737

Reaction notes

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