Hydrochloric Acid → HCID 178441881, compound

Participants

Reaction Conditions

Reaction Steps

To the obtained white powder of trimethylacetylsemicarbazide was added 1500 ml of a 5% aqueous potassium hydroxide solution, and the mixture was heated to 100° C. with stirring. After the contents were completely dissolved, the solution was further heated at 100° C. for one hour, and the reaction mixture was cooled and then neutralized by an addition of conc. hydrochloric acid. The white precipitates formed were collected by filtration, washed with water, and then dried under reduced pressure to give 64 g of 3-tert-butyl-1H-1,2,4-triazole-5-one as white powder (yield 45%).

Provenance & Evidence