Hydrochloric Acid → HCID 178441881, compound

Temperature

100 °C

To the obtained white powder of trimethylacetylsemicarbazide was added 1500 ml of a 5% aqueous potassium hydroxide solution, and the mixture was heated to 100° C. with stirring. After the contents were completely dissolved, the solution was further heated at 100° C. for one hour, and the reaction mixture was cooled and then neutralized by an addition of conc. hydrochloric acid. The white precipitates formed were collected by filtration, washed with water, and then dried under reduced pressure to give 64 g of 3-tert-butyl-1H-1,2,4-triazole-5-one as white powder (yield 45%).

1. dissolutionAfter the contents were completely dissolved
2. temperaturethe solution was further heated at 100° C. for one hour
3. temperaturethe reaction mixture was cooled
4. customThe white precipitates
5. customformed
6. filtrationwere collected by filtration
7. washwashed with water
8. customdried under reduced pressure

ORD record

ord-e129e9f03ecf4c4eb933fdd34ef260eb

Source dataset

uspto-grants-1994_02

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05286738