4-Nitrobenzoic Acid → HCID 19020587, compound

HRID 1975344Notes

Reaction equation

HRID 1975344 reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][N:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)=[CH:16][CH:15]=1>CN(C)C=O>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([C:8]([N:25]2[CH2:24][CH2:23][N:22]([CH2:21][CH2:20][C:17]3[CH:18]=[CH:19][C:14]([Cl:13])=[CH:15][CH:16]=3)[CH2:27][CH2:26]2)=[O:10])=[CH:11][CH:12]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 61084-Nitrobenzoic AcidHCID 122357141-[2-(4-Chlorophenyl)ethyl]piperazine

Product 1

HCID 19020587HCID 19020587, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The 1-(4-nitrobenzoyl)-4-[2-(4-chlorophenyl)ethyl]piperazine is prepared from 4-nitrobenzoic acid and 1-[(4-chlorophenyl)ethyl]piperazine in N,N-dimethylformamide in the presence of N,N-carbonylimidazole. It melts at 109°-110°.

Sources & evidence

ORD record
ord-3a2d9d572c774cc08e43645e5a8e4733
Source dataset
uspto-grants-1994_02
Patent number
US05286728

Reaction notes

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