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HRID1975351

反应详情

EQUATION

反应方程式

HRID 1975351 的结构方程式

REACTANTS

反应物

3
结构：CNc1ccc(C(=O)O)cc1
HCID66345

Benzoic acid, 4-(methylamino)-

C8H9NO2

结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

结构：CSc1ccc(CCN2CCNCC2)cc1
HCID53859945

未命名化合物

PRODUCTS

生成物

1
结构：CNc1ccc(C(=O)N2CCN(CCc3ccc(SC)cc3)CC2)cc1
HCID54117481

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The 1-(4-methylaminobenzoyl)-4-[2-(4-methylmercaptophenyl)ethyl]piperazine is prepared from 1.66 g of 4-methylaminobenzoic acid, 1.95 g of N,N-carbonyldiimidazole and 2.35 g of 1-[2-(4-methylmercaptophenyl)ethyl]piperazine in dimethylformamide at 85°. The base is purified via the hydrochloride (m.p. 185°, decomp.) and melts at 120°-121°.

WORKUP

后处理

  1. customThe base is purified via the hydrochloride (m.p. 185°, decomp.) and melts at 120°-121°