Hydrochloric Acid → HCID 178458056, compound

HRID 1975403Notes

Reaction equation

HRID 1975403 reaction equation
[CH2:1]([C:3]1[N:4](CC2C=CC=CC=2)[CH2:5][C:6]2[CH:19]=[CH:18][CH:17]=[CH:16][C:7]=2[CH:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:9]=1)[CH3:2].Cl>>[C:10]1([CH2:8][C:7]2[CH:16]=[CH:17][CH:18]=[CH:19][C:6]=2[CH2:5][NH:4][C:3](=[NH:9])[CH2:1][CH3:2])[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 14978281HCID 14978281, compound

Product 1

HCID 178458056HCID 178458056, compound

Procedure

By a process substantially similar to that of Example 2, 2.82 g (7.5 mmol) of 4,5-dihydro-3-ethyl-1-phenyl-4-(phenylmethyl)-1H-2,4-benzodiazepine was converted to 1.1 g of product as the hydrochloride after recrystallization from isopropyl alcohol/ether, mp 172-174.

Workup

  1. customafter recrystallization from isopropyl alcohol/ether, mp 172-174

Sources & evidence

ORD record
ord-6b1dc9528c634e7ab9d6cfc24d8638b1
Source dataset
uspto-grants-1994_02
Patent number
US05286752

Reaction notes

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