Ethanol → HCID 19099231, compound

HRID 1975466Notes

Reaction equation

HRID 1975466 reaction equation
[C:1]([CH2:3][C:4]1[N:5](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:6]=[CH:7][N:8]=1)#[N:2].C(O)C.[F:31][C:32]([F:37])([F:36])[C:33]([OH:35])=[O:34]>>[F:31][C:32]([F:37])([F:36])[C:33]([OH:35])=[O:34].[C:1]([CH2:3][C:4]1[NH:5][CH:6]=[CH:7][N:8]=1)#[N:2]

Participants

4

Reactant 3

HCID 702EthanolHCID 6422Trifluoroacetic acidHCID 19099328HCID 19099328, compound

Product 1

HCID 19099231HCID 19099231, compound

Procedure

2-Cyanomethyl-1-tritylimidazole (25 g) was dissolved in trifluoroacetic acid (70 ml). After stirring for 3 hours, to the reaction mixture was added ethanol (70 ml) and the solvent was removed in vacuo. Resulting solid was collected and washed with diisopropyl ether to give 2-cyanomethylimidazole trifluoroacetate (12.67 g).

Workup

  1. customthe solvent was removed in vacuo
  2. customResulting solid
  3. customwas collected
  4. washwashed with diisopropyl ether

Sources & evidence

ORD record
ord-761a13fdf4c545beae33a3d4adaafbb0
Source dataset
uspto-grants-1994_02
Patent number
US05286721

Reaction notes

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