Chloroform → HCID 19099228, compound

Participants

Reaction Steps

Into the suspension of 2-cyanomethylimidazole trifluoroacetate (7 g) in a mixture of chloroform (25 ml) and ethanol (2.42 ml) was absorbed hydrogen chloride gas (2.54 g) at 0° C. The resulting mixture was allowed to stand at 0° C. for 7 days. The residue was triturated with diisopropyl ether to give ethyl 2-(imidazol-2-yl)-acetimidate dihydrochloride (6.28 g).

Provenance & Evidence