Methyl iodide → HCID 22406599, compound

HRID 1975687Notes

Reaction equation

HRID 1975687 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.[CH3:12]I.[CH2:14](I)[CH3:15]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]([CH3:12])([CH2:14][CH3:15])[C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 6340IodoethaneHCID 88310(3-Methoxyphenyl)acetonitrile

Product 1

HCID 22406599HCID 22406599, compoundYield 8%

Procedure

The procedures described in the portion of Example 1 which is concerned with the preparation of starting materials were repeated except that 3-methoxyphenylacetonitrile was alkylated in turn with methyl iodide and ethyl iodide. The 2-(3-methoxyphenyl)-2-methylbutyronitrile so obtained was treated with boron tribromide to give the required starting material in an overall yield of 8% as a gum.

Workup

  1. customis concerned with the preparation of starting materials

Sources & evidence

ORD record
ord-70f3437712ff47dbb974169d64aa0d28
Source dataset
uspto-grants-1994_02
Patent number
US05288742

Reaction notes

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