Water → HCID 19098601, compound

HRID 1975715Notes

Reaction equation

HRID 1975715 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=O.[CH3:13][C:14](=[O:19])[CH2:15][C:16](=[O:18])[CH3:17].O>FC(F)(F)C(O)=O>[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[C:15]([C:14](=[O:19])[CH3:13])[C:16](=[O:18])[CH3:17]

Participants

5

Reactant 3

HCID 962WaterHCID 31261AcetylacetoneHCID 123067o-(Trifluoromethyl)benzaldehyde

Product 1

HCID 19098601HCID 19098601, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

To a solution of 2-trifluoromethylbenzaldehyde (8,7 g) and 2,4-pentanedione (5,01 g) in trifluoroacetic acid (10 ml) thionylchloride (4 ml) and catalytic amount of water (0,05 ml) were added at room temperature. The solution was stirred over night at 20°? C. The solvent was evaporated and the residue was distilled in vacuo, bp 110° C./1.5 mbar. Yield 5.3 g (41 %).

Workup

  1. customThe solvent was evaporated
  2. distillationthe residue was distilled in vacuo, bp 110° C./1.5 mbar

Sources & evidence

ORD record
ord-6df4b7009ea74173a6690dfeba3a7d96
Source dataset
uspto-grants-1994_02
Patent number
US05288750

Reaction notes

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