Thionyl Chloride → HCID 53883256, compound

HRID 1975865Notes

Reaction equation

HRID 1975865 reaction equation
[CH3:1][C@@H:2]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3]O.S(Cl)([Cl:14])=O>>[CH3:1][C@@H:2]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][Cl:14]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 11804940(S)-2-methyl-3-phenylpropan-1-ol

Product 1

HCID 53883256HCID 53883256, compound

Procedure

In accordance with the general procedure described in Example 8 (a), 22.5 g (0.15 mol) of (S)-2-methyl-3-phenylpropanol are reacted with 20.2 g (0.17 mol) of thionyl chloride, and the crude product is distilled under a high vacuum (18 torr) to give (b) (b.p. 110°-112° C.) as a colourless oil.

Workup

  1. distillationthe crude product is distilled under a high vacuum (18 torr)

Sources & evidence

ORD record
ord-43d5fd277fdc4062bb243f7770933b6e
Source dataset
uspto-grants-1994_02
Patent number
US05288928

Reaction notes

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