Piperidine → S-Fenpropidin
Reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C@H:12]([CH3:15])[CH2:13]Cl)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[CH3:15][C@H:12]([CH2:13][N:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[CH2:11][C:8]1[CH:9]=[CH:10][C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:6][CH:7]=1Participants
3
Procedure
The reaction of (a) with piperidine gives the novel compound (S)-fenpropidine.
Sources & evidence
- ORD record
- ord-7f8abd136f3b47dda8a11793cb0e13e9
- Source dataset
- uspto-grants-1994_02
- Patent number
- US05288928
Reaction notes
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