Diethyl Ether → HCID 22237792, compound

HRID 1975897Notes

Reaction equation

HRID 1975897 reaction equation
[CH3:1][C:2]1[C:3]([CH3:12])([CH3:11])[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][I:22])(=[O:15])[CH3:14].CCOCC>ClC1C=CC=CC=1Cl>[I-:22].[CH3:1][C:2]1[C:3]([CH3:12])([CH3:11])[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N+:6]=1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][O:16][C:13]([CH3:14])=[O:15]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 154273H-Indole, 2,3,3-trimethyl-HCID 10988867HCID 10988867, compound

Product 1

HCID 22237792HCID 22237792, compound

Reagents, catalysts & solvents 1

HCID 72391,2-DichlorobenzeneSolvent

Conditions

Temperature
120 °C

Procedure

A mixture of 2,3,3-trimethyl-3H-benzo[b]azole (2.39 g, 15 mmol) and 5-iodopentyl acetate (3.84 g, 15 mmol) in 1,2-dichlorobenzene (15 ml) were heated at 120° C. for 6 h and then cooled to ambient temperature. The mixture was then dripped into Et2O which precipitated the title compound as a red gum which was collected and used without any further purification in subsequent reactions.

Workup

  1. temperaturecooled to ambient temperature
  2. customprecipitated the title compound as a red gum which
  3. customwas collected
  4. customused without any further purification in subsequent reactions

Sources & evidence

ORD record
ord-b2c17977f2274bc682c2742ccb29f7d7
Source dataset
uspto-grants-2001_05
Patent number
US06225050B1

Reaction notes

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