HCID 21999979, compound → HCID 21999989, compound

Participants

Reaction Conditions

Reaction Steps

A solution of sodium nitrite (0.47 g) in 5 ml of water was added dropwise to a stirred solution of 4-cyano-2-hydrazinocarbonyl-5-methyl-thiophene-3-sulfonamide (1.6 g) in 38 ml of 1 M hydrochloric acid at 0° C. The resulting mixture was stirred for 30 min at 0° C. and then filtered. The filter cake was washed with water and dried in vacuum to give 1.35 g of the title compound; 1H-NMR (DMSO-d6), δ(ppm): 7.75 (br, 1H, NH2), 2.75 (s, 1H, CH3).

Provenance & Evidence