Phenylboronic Acid → HCID 20329674, compound

HRID 1975944Notes

Reaction equation

HRID 1975944 reaction equation
[C:1]1(B(O)O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:10][C:11]1[CH:16]=[CH:15][C:14](Br)=[CH:13][C:12]=1[CH3:18]>>[F:10][C:11]1[CH:16]=[CH:15][C:14]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:13][C:12]=1[CH3:18]

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 1235275-Bromo-2-fluorotoluene

Product 1

HCID 20329674HCID 20329674, compound

Procedure

In the case of Q10-Br, the desired 2-fluoro-5-phenyl-toluene (S1=F) was prepared from phenylboronic acid and 2-fluoro-5-bromo-toluene via a Suzuki reaction, analogously to procedure A2. See scheme A3.

Sources & evidence

ORD record
ord-cd028637484d4b0e8c078d939b6bc0e2
Source dataset
uspto-grants-2001_05
Patent number
US06225312B1

Reaction notes

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