HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 11449803, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl 5-bromo-2-(4-methyl-1-piperazinyl)-4-pyridinecarboxylate | HCID 11221145 | — |
| Product | HCID 11449803 | HCID 11449803 | 100% |
Reaction Steps
A solution of 1.45 g (5.8 mmol) 5-bromo-2-(4-methyl-piperazin-1-yl)-isonicotinic acid ethyl ester in 25 ml methylamin (33% in ethanol) was heated in a high pressure vessel at 85° for 12 h. Evaporation of the solvent afforded 1.81 g (100%) of the title compound as yellow crystals. M.p. 122-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225316B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-1b34ab7a223b4be987d88aadaead1210 |
| Source note | uspto-grants-2001_05 |