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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1975978Generated: October 26, 2026

6-Chloro-2,3-dihydro-1h-indole → 4-(6-Chloro-2,3-dihydro-indol-1-yl)-6-phenyl-quinazoline

https://huagongshe.com/reaction/1975978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2,3-dihydro-1h-indoleHCID 258567—
Reactant6-Phenylquinazolin-4(3H)-oneHCID 135741302—
Product4-(6-Chloro-2,3-dihydro-indol-1-yl)-6-phenyl-quinazolineHCID 22000108—

Reaction Steps

The title compound was prepared in a manner analogous in the method of Example 4 using 6-Phenyl-3H-quinazolin-4-one (250 mg, 1.124 mmol) and 6-chloroindoline (172 mg, 1.124 mmol)). Three hundred eighty-nine milligrams (88%) of a yellow solid was isolated from the reaction mixture.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06225318B1
Source datasetuspto-grants-2001_05
ORD IDord-8970a41501074764ad2367d19b632b4f
Source noteuspto-grants-2001_05