HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → (3-Ethynyl-phenyl)-(6-pyridin-2-ylethynyl-quinazolin-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Ethynylpyridine | HCID 137268 | — |
| Reactant | (3-Ethynyl-phenyl)-(6-iodo-quinazolin-4-yl)-amine | HCID 22000138 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (3-Ethynyl-phenyl)-(6-pyridin-2-ylethynyl-quinazolin-4-yl)-amine | HCID 53905550 | — |
Reaction Steps
The title compound was synthesized according to the method of Example 2 using (3-Ethynyl-phenyl)-(6-iodo-quinazolin-4-yl)-amine (125 mg, 0.506 mmol), 2-ethynyl-pyridine (66 mg, 0.505 mmol) and diethyl amine (72 mg, 0.99 mmol) in 2 mL, of DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225318B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-5f485029b2a7405eb08c8ee661cf2918 |
| Source note | uspto-grants-2001_05 |