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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1976013Generated: October 31, 2026

2-Naphthalenesulfonyl chloride → ethyl 1-naphthalen-2-ylsulfonylpiperidine-3-carboxylate

https://huagongshe.com/reaction/1976013

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Naphthalenesulfonyl chlorideHCID 7125—
ReactantEthyl nipecotateHCID 98969—
Productethyl 1-naphthalen-2-ylsulfonylpiperidine-3-carboxylateHCID 378556462%

Reaction Steps

Using an analogous procedure to that described in Example 2, ethyl piperidine-3-carboxylate was reacted with 2-naphthylsulphonyl chloride to give ethyl 1-(2-naphthylsulphonyl)piperidine-3-carboxylate in 62% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06225309B1
Source datasetuspto-grants-2001_05
ORD IDord-f7c6bad792804e6996e7bf24622f8e6e
Source noteuspto-grants-2001_05