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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1976224Generated: November 1, 2026

1-(2-Nitrophenyl)-L-proline → ZINC00251459

https://huagongshe.com/reaction/1976224

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Nitrophenyl)-L-prolineHCID 28119399—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
ProductZINC00251459HCID 77011383.7%

Reaction Steps

The 1-(2-nitrophenyl)-L-proline (1.56 g) obtained in Reference Example 1 was catalytically reduced at ordinary temperature, in the presence of 0.6 g of a 10% palladium-carbon catalyst, in 150 ml of methanol. After completion of the reaction, the catalyst was removed and then the reaction solution was concentrated to dryness to give 1.04 g (yield 83.3%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06225306B1
Source datasetuspto-grants-2001_05
ORD IDord-beca15ac9cae4d7cb2f087c8a599dff0
Source noteuspto-grants-2001_05