HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Nitrophenyl)-L-proline → ZINC00251459
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Nitrophenyl)-L-proline | HCID 28119399 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | ZINC00251459 | HCID 770113 | 83.7% |
Reaction Steps
The 1-(2-nitrophenyl)-L-proline (1.56 g) obtained in Reference Example 1 was catalytically reduced at ordinary temperature, in the presence of 0.6 g of a 10% palladium-carbon catalyst, in 150 ml of methanol. After completion of the reaction, the catalyst was removed and then the reaction solution was concentrated to dryness to give 1.04 g (yield 83.3%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225306B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-beca15ac9cae4d7cb2f087c8a599dff0 |
| Source note | uspto-grants-2001_05 |