HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 10142602, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 10073901 | HCID 10073901 | — |
| Product | HCID 10142602 | HCID 10142602 | — |
Reaction Steps
According to the procedure of Example 118, using 1-methylpiperazine instead of diethylamine, 2-[{[4-(2-butynyloxy)phenyl]sulfonyl}(3-chloropropyl)-amino-3-3-methylbutanoate was converted into 2-{{[4-(2-butynyloxy)phenyl]sulfonyl}-[3-(4-methyl-1-piperazinyl)propyl]amino}-N-hydroxy-3-methylbutanamide, which was converted into the corresponding hydrochloride salt with ethereal HCl solution to provide an off-white solid. Electrospray Mass Spec 481.4 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225311B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-40f65fcec90145f3a3e4732bfedf4877 |
| Source note | uspto-grants-2001_05 |