HCID 21998549, compound → HCID 21998547, compound

HRID 1976530Notes

Reaction equation

HRID 1976530 reaction equation
[CH3:1][N:2]([CH3:22])[C:3](=[O:21])[C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:12])[NH2:11])=[CH:6][C:5]=1[S:13](=[O:20])(=[O:19])[NH:14]C(C)(C)C>FC(F)(F)C(O)=O>[CH3:1][N:2]([CH3:22])[C:3](=[O:21])[C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:12])[NH2:11])=[CH:6][C:5]=1[S:13](=[O:19])(=[O:20])[NH2:14]

Participants

3

Reactant 1

HCID 21998549HCID 21998549, compound

Product 1

HCID 21998547HCID 21998547, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

At room temperature, 1.0 g (3.1 mmol) of N,N-dimethyl-2-tert-butylsulfamoyl-4-carbamoylbenzamide in 10 ml of trifluoroacetic acid was stirred for 2.5 h. The mixture was concentrated and the residue was triturated with diethyl ether, filtered off with suction and dried. This gave 0.53 g (63% of theory) of N,N-dimethyl-4-carbamoyl-2- sulfamoylbenzamide of m.p. 202-205° C.

Workup

  1. concentrationThe mixture was concentrated
  2. customthe residue was triturated with diethyl ether
  3. filtrationfiltered off with suction
  4. customdried

Sources & evidence

ORD record
ord-9ee8e0f4b01641729c7855abea695d1f
Source dataset
uspto-grants-2001_05
Patent number
US06228808B1

Reaction notes

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