Water → HCID 69842380, compound

Participants

Reaction Steps

Intermediate 6 (31 g), potassium carbonate (71 g), water (930 ml) and ethanol (930 ml) were warmed at 60° C. for 3 h. The ethanol was removed in vacuo and the aqueous residue extracted with ethyl acetate (3×300 ml). The combined extracts were washed with brine and dried (MgSO4) and concentrated in vacuo to give the title compound as a brown oil (17.5 g).

Provenance & Evidence