HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1976737Generated: November 1, 2026
HCID 21906498, compound → (6-trifluoroacetylamino-1-methyl-1H-indol-3-yl)-oxo-acetyl chloride
https://huagongshe.com/reaction/1976737
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 21906498 | HCID 21906498 | — |
| Reactant | 1-Methyl-6-trifluoroacetylaminoindole | HCID 21999022 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (6-trifluoroacetylamino-1-methyl-1H-indol-3-yl)-oxo-acetyl chloride | HCID 21999020 | — |
Reaction Steps
200 mg of 1-methyl-6-trifluoroacetylaminoindole was taken into 5 mL ether and cooled to 0° C. It was treated with 0.485 mL 2.0 M oxalyl chloride/methylene dichloride and stirred at 0° C. for 2 h. The yellow crystals were collected and washed with ether and dried in vacuo to yield 240 mg of (6-trifluoroacetylamino-1-methyl-1H-indol-3-yl)-oxo-acetyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06228877B1 |
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| Source dataset | uspto-grants-2001_05 |
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| ORD ID | ord-a8200d21b8b249c785a4d4de3b95bcfd |
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| Source note | uspto-grants-2001_05 |
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