Acetic Anhydride → HCID 21999134, compound

HRID 1976755Notes

Reaction equation

HRID 1976755 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1[C:19]([CH3:21])([CH3:20])[CH2:18][CH2:17][CH2:16][C:15]=1[CH3:22].[C:23](OC(=O)C)(=[O:25])[CH3:24]>N1C=CC=CC=1>[C:23]([O:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1[C:19]([CH3:21])([CH3:20])[CH2:18][CH2:17][CH2:16][C:15]=1[CH3:22])(=[O:25])[CH3:24]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 21999128HCID 21999128, compound

Product 1

HCID 21999134HCID 21999134, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a solution of 1-(12-hydroxydodecyl)-2,6,6-trimethyl-1-cyclohexene (316 mg, 1.026 mmol) were added acetic anhydride (7 ml) and pyridine (7 ml). The mixture was stirred at room temperature for 1 hour, then quenched with HCl 5%, extracted with ether, washed with water, dried with MgSO4 and concentrated in vacuo to obtain 1-(12-acetoxydodecyl)-2,6,6-trimethyl-1-cyclohexene as a colorless oil (353 mg, 98%).

Workup

  1. customquenched with HCl 5%
  2. extractionextracted with ether
  3. washwashed with water
  4. dry with materialdried with MgSO4
  5. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-49701c8bc69a4650b1f87fd7adde7f7d
Source dataset
uspto-grants-2001_05
Patent number
US06228893B1

Reaction notes

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