Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzhydrol | HCID 7037 | — |
| Reactant | (Trifluoromethyl)benzene | HCID 7368 | — |
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | 1-Octen-3-Ol | HCID 18827 | — |
| Reactant | Hexafluoroacetone trihydrate | HCID 36719 | — |
| Catalyst | Cobalt diacetate | HCID 6277 | — |
| Product | 1,2-Epoxy-3-octanol | HCID 10290854 | 40% |
Reaction Steps
A mixture of 3mmol of 1-octen-3-ol, 15mmol of benzhydrol, 0.3 mmol of N-hydroxyphthalimide, 0.0015 mmol of cobalt (II) acetate, 0.6 mmol of hexafluoroacetone trihydrate, and 3 ml of trifluoromethylbenzene was stirred at 60° C. under an oxygen atmosphere (1 atm) for 24 hours. Gas chromatographic analysis of products in a reaction mixture revealed that 1-octen-3-ol was converted, at a rate of 43%, into 1,2-epoxy-3-octanol (yield: 40%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06229023B1 |
|---|
| Source dataset | uspto-grants-2001_05 |
|---|
| ORD ID | ord-b76c200635054022a293f89e44cb585f |
|---|
| Source note | uspto-grants-2001_05 |
|---|
