HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Amino-8-oxabicyclo[3.2.1]octane-3-carboxylic acid benzyl ester hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(Benzhydrylideneamino)-8-oxabicyclo[3.2.1]octane-3-carboxylic acid benzyl ester | HCID 54051614 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-Amino-8-oxabicyclo[3.2.1]octane-3-carboxylic acid benzyl ester hydrochloride | HCID 69921987 | — |
Reaction Steps
A two-phase mixture of 3-(benzhydrylideneamino)-8-oxabicyclo[3.2.1]octane-3-carboxylic acid benzyl ester (3.9 mmole) in aqueous 1N hydrochloric acid solution (100 mL) and diethyl ether (100 mL) is stirred at room temperature overnight. The aqueous layer is concentrated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06229025B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-08b2206697d84ed8a2fdf522402b0b72 |
| Source note | uspto-grants-2001_05 |