Methyl L-phenylalaninate hydrochloride → L-Phenylalanine

HRID 1976973Notes

Reaction equation

HRID 1976973 reaction equation
Cl.C[O:3][C:4](=[O:14])[C@H:5]([CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[NH2:6].BrC1C=CC(OC)=CC=1C(O)=O>>[NH2:6][C@H:5]([C:4]([OH:14])=[O:3])[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 75736Methyl L-phenylalaninate hydrochlorideHCID 899062-Bromo-5-methoxybenzoic acid

Product 1

HCID 6140L-Phenylalanine

Procedure

N-(2-Bromo-5-methoxybenzoyl)-4-[(2,4-dimethyl-3-pyridinyl)carbonyl]amino]-L-phenylalanine was prepared from 4-[(2,4-dimethyl-3-pyridyl)carbonyl]amino]-L-phenylalanine methyl ester hydrochloride and 2-bromo-5-methoxybenzoic acid using the general method described in example 107. MS (M+H) 526 (1 Br).

Sources & evidence

ORD record
ord-e0848ca9175342d2960c6f7a56fa0a85
Source dataset
uspto-grants-2001_05
Patent number
US06229011B1

Reaction notes

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