Hydroxide → 4-(4-Aminophenoxy)-2-{[4-(1-methylpiperazin-4-yl)piperidin-1-yl]carbonylamino}pyridine

HRID 197701Notes

Reaction equation

HRID 197701 reaction equation
[C+4:38].[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[NH:16][c:17]3[n:18][cH:19][cH:20][c:21]([O:23][c:24]4[cH:25][cH:26][c:27]([N+:30]([O-:31])=[O:32])[cH:28][cH:29]4)[cH:22]3)[CH2:12][CH2:13]2)[CH2:6][CH2:7]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[OH-:39].[OH-:41].[OH-:42].[OH-:43].[OH-:44].[OH-:45].[Pd+2:40]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[NH:16][c:17]3[n:18][cH:19][cH:20][c:21]([O:23][c:24]4[cH:25][cH:26][c:27]([NH2:30])[cH:28][cH:29]4)[cH:22]3)[CH2:12][CH2:13]2)[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 961Hydroxide6×HCID 8028TetrahydrofuranHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 231531552-{[4-(1-Methylpiperazin-4-yl)piperidin-1-yl]carbonylamino}-4-(4-nitrophenoxy)pyridineHCID 178420935HCID 178420935, compound

Product 1

HCID 231533634-(4-Aminophenoxy)-2-{[4-(1-methylpiperazin-4-yl)piperidin-1-yl]carbonylamino}pyridine

Sources & evidence

ORD record
ord-8b6bbccf0ac64c2a840e742925387ed3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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