HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → HCID 21997244, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | 3,6-Dichloropyridazine | HCID 67331 | — |
| Reactant | (Octahydro-1H-pyrido[1,2-A]pyrazin-7-YL)methanol | HCID 12985539 | — |
| Product | HCID 21997244 | HCID 21997244 | — |
Reaction Steps
A mixture of (7RS,9aSR)-7-hydroxymethyl-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazine (U.S. Pat. No. 5,326,874) and 3,6-di-chloropyridazine were combined according to Preparation 3. The product from this reaction was coupled with 4-fluorophenol according to Example 1 to give the title compound. mp (—HCl) 255° C. (dec). HRMS calc for C19H22ClFN4O: 376.1461, found: 376.1458.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06231833B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-765b6c8467bd43e880e517c34c2b7b00 |
| Source note | uspto-grants-2001_05 |