HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 20654294, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 3,6-Dichloropyridazine | HCID 67331 | — |
| Reactant | (Octahydro-1H-pyrido[1,2-A]pyrazin-7-YL)methanol | HCID 12985539 | — |
| Product | HCID 20654294 | HCID 20654294 | — |
Reaction Steps
A mixture of (7RS,9aSR)-7-hydroxymethyl-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazine (U.S. Pat. No. 5,326,874) and 3,6-dichloropyridazine were combined according to Preparation 3. The product from this reaction was coupled with phenol according to Example 1 to give the title compound. mp (—HCl) >265° C. (dec). HRMS calcd for C19H23ClN4O: 358.1555, found: 358.1550.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06231833B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-8118f06a171e4896be606f4a7ab5f6db |
| Source note | uspto-grants-2001_05 |