HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Hydroxy-4-biphenylcarboxylic acid → Methyl 4'-hydroxy(1,1'-biphenyl)-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Hydroxy-4-biphenylcarboxylic acid | HCID 301556 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Product | Methyl 4'-hydroxy(1,1'-biphenyl)-4-carboxylate | HCID 1490289 | — |
Reaction Steps
A solution of 4-(4′-hydroxyphenyl)benzoic acid (25.6 g) in 10% hydrochloric acid-methanol was stirred for 3 days at room temperature. Then the solvent was evaporated in vacuo and the residue was triturated with toluene-ethyl acetate (20:1) to afford methyl 4-(4′-hydroxyphenyl)benzoate (26.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06232290B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-930c20934dd64b0f8000cd77c91c6aab |
| Source note | uspto-grants-2001_05 |