HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-4-sulfonic acid → (1,1'-Biphenyl)-4-sulphonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-4-sulfonic acid | HCID 16673 | — |
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Solvent | Water | HCID 962 | — |
| Product | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
Reaction Steps
4-Biphenyl sulfonic acid (2.4 g, 10 mmol) was heated to 100 C. with phosphorus pentachloride (2.1 g, 10 mmol) overnight. The reaction was cooled to RT, diluted with water, filtered and washed with water. The solid was then triturated with EtOAc-ether and the beige solid was used in the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06232342B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-0067f39eff8b46d1aaa637986126e150 |
| Source note | uspto-grants-2001_05 |