HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(3,5-Dichloro-2-hydroxy-4-methylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Amino-4,6-dichloro-5-methylphenol | HCID 170224 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-(3,5-Dichloro-2-hydroxy-4-methylphenyl)acetamide | HCID 13796880 | — |
Reaction Steps
The product from Example 9, Stage 1a (4.8 g), was stirred in acetic acid (20 ml) and acetic anhydride (5 ml) was added in one portion. Stirring was continued for 1hour after the initially exothermic reaction had subsided. The product was isolated by filtration and recrystallised from aqueous ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235096B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-50c96833c52540fa94a6694323f546a3 |
| Source note | uspto-grants-2001_05 |