HCID 86753223, 화합물 → HCID 86753222, 화합물

HRID 1977589노트

반응식

HRID 1977589 반응식
[CH2:1]([C:4]([C@@H:6]([C@H:8]([C@H:19]([C@@H:21]([CH2:23][OH:24])[OH:22])[OH:20])[O:9][CH:10](OC(C)(C)C)[C:11]([OH:13])=[O:12])[OH:7])=[O:5])[CH:2]=[CH2:3]>[OH-].[Na+]>[CH2:1]([C:4]([C@@H:6]([C@H:8]([C@H:19]([C@@H:21]([CH2:23][OH:24])[OH:22])[OH:20])[O:9][CH2:10][C:11]([OH:13])=[O:12])[OH:7])=[O:5])[CH:2]=[CH2:3]

참가 물질

3

반응물 1

HCID 86753223HCID 86753223, 화합물

생성물 1

HCID 86753222HCID 86753222, 화합물수율 113%

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

Compound 7 (7.8 g) was dissolved in 2N NaOH solution and stirred for 2 hr. The reaction mixture was acidified with Dowex-H resin and the resin was removed by filtration. The filtrate was lyophilized to give 1-C-allyl-3-O-carboxymethylgalactose (7.0 g). 1N NMR (CD3OD): δ, 2.38-2.42, 2H; 3.28-3.31, m, 1H; 3.44-3.47, dd, 2H; 3.63-3.67,m, 2H; 3.98-4.02, m, 1H; 4.11-4.15,m, 1H; 4.22-4.25,m, 1H; 4.95-5.00, and 5.10-5.15,dd, 2H, CH2CH═CH2; 5.75-5.85, m, 1H, CH2CH═CH2: 13C NMR (CD3OD): 176.52 (COOH); 136.67, 116.89, 81.98, 79.79, 76.00, 73.50, 68.60, 68.56, 67.59, 62.05, 30.70: [α]D=+66.82 (c 0.214, methanol).

후처리

  1. customthe resin was removed by filtration

출처 및 근거

ORD 기록
ord-98293937852241408865359f8c411a3a
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06235720B1

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