HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxylic acid, monohydrate → HCID 135815254, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Reactant | 5-[(4-Aminophenyl)methyl]-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one | HCID 135815262 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 135815254 | HCID 135815254 | — |
Reaction Steps
10% w/w Palladium on charcoal (87 mg) was added to a solution of 5-(4-aminobenzyl)-1-methyl-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-7-one (870 mg, 0.00293 mol) and glyoxylic acid hydrate (260 mg, 0.0035 mol) in methanol (20 ml) and the mixture hydrogenated at room temperature at 50 p.s.i. for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235742B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-d9182cbe95374082b02e1cfd578ba641 |
| Source note | uspto-grants-2001_05 |