HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetanilide → N-Phenyl-N-thiophen-3-yl-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetanilide | HCID 904 | — |
| Reactant | 3-Bromothiophene | HCID 13383 | — |
| Product | N-Phenyl-N-thiophen-3-yl-acetamide | HCID 16640263 | 25.2% |
Reaction Steps
Using acetanilide (6.0 g) and 3-bromothiophene (14.5 g), a reaction was made in the same manner as in 1) of Production Example 2. The subsequent purification by silica gel column chromatography (developing solvent, ethyl acetate:hexane=1:4) produced N-(3-thienyl)acetanilide (2.43 g; yield, 25%) as a pale brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235730B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-dee149cd1efa46b79296b1ee29f3b32f |
| Source note | uspto-grants-2001_05 |