Triethylamine → HCID 18005096, compound

HRID 1977737Notes

Reaction equation

HRID 1977737 reaction equation
[C:1]1([C:7]2[CH:8]=[C:9]([C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[CH:10]=[C:11]([CH:13]=2)[NH2:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[C:21]([O:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=[O:22].C(N(CC)CC)C>C(Cl)Cl>[C:1]1([C:7]2[CH:8]=[C:9]([C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[CH:10]=[C:11]([NH:12][C:21](=[O:22])[O:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH:13]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 15891Phenyl chloroformateHCID 219955595-(Pyridin-3-yl)-[1,1'-biphenyl]-3-amine

Product 1

HCID 18005096HCID 18005096, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound (0.289 g, 100%) was prepared by methodology of description 67 using 5-phenyl-3-(pyrid-3-yl)aniline (0.194 mg, 0.79 mmol), phenyl chloroformate (0.12 ml, 0.87 mmol) and triethylamine (0.12 ml, 0.81 mmol) in DCM (10 ml)

Sources & evidence

ORD record
ord-4a157d0e6e40485abbcb3a6f3478407b
Source dataset
uspto-grants-2001_05
Patent number
US06235758B1

Reaction notes

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