2-Bromoethyl methyl ether → HCID 131722575, compound

HRID 1978073Notes

Reaction equation

HRID 1978073 reaction equation
O1CCCCC1[O:7][NH:8][C:9]([C@H:11]([C@@H:21]([CH2:30][CH:31]([CH3:33])[CH3:32])[C:22]([NH:24][NH:25][S:26]([CH3:29])(=[O:28])=[O:27])=[O:23])[CH2:12]/[CH:13]=[CH:14]/[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:10].[CH3:34][O:35][CH2:36][CH2:37]Br>>[OH:7][NH:8][C:9]([C@H:11]([C@@H:21]([CH2:30][CH:31]([CH3:32])[CH3:33])[C:22]([NH:24][N:25]([S:26]([CH3:29])(=[O:27])=[O:28])[CH2:37][CH2:36][O:35][CH3:34])=[O:23])[CH2:12]/[CH:13]=[CH:14]/[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)=[O:10]

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 86756723HCID 86756723, compound

Product 1

HCID 131722575HCID 131722575, compound

Procedure

The starting material was prepared in an analogous manner to that described in Example 15, part (iii), starting from (E)-2(R)-[1(S)-[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]-4-phenyl-3-butenyl]-2′-(methanesulphonyl)-4-methylvalerohydrazide and 2-bromoethyl methyl ether.

Workup

  1. customThe starting material was prepared in an analogous manner to that

Sources & evidence

ORD record
ord-5807c8f17fec451baf6aadbb18128802
Source dataset
uspto-grants-2001_05
Patent number
US06235787B1

Reaction notes

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