Methanesulfonic Acid → HCID 86756745, compound

Participants

Reaction Steps

In a manner analogous to that described in the first paragraph of Example 2, but using methanesulphonic acid in place of p-toluenesulphonic acid, starting from 0.2 g of (E)-2(R)-[1(S)-[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]-4-phenyl-3-butenyl]-2′-(methanesulphonyl)-4-methyl-2′-[(3-pyridyl)methyl]valerohydrazide there was obtained 0.177 g of (E)-2(R)-[1(S)-(hydroxycarbamoyl)-4-phenyl-3-butenyl]-2′-(methanesulphonyl)-4-methyl-2′-[(3-pyridyl)methyl]valerohydrazide methanesulphonate in the form of an orange solid.

Provenance & Evidence