Methyl 3-hydroxyadamantane-1-carboxylate → 1-Methoxycarbonyl-3-acryloyloxyadamantane

HRID 1978129Notes

Reaction equation

HRID 1978129 reaction equation
[C:1](OCC12CC3CC(CC(O)(C3)C1)C2)(=[O:4])[CH:2]=[CH2:3].[CH3:18][O:19][C:20]([C:22]12[CH2:31][CH:26]3[CH2:27][CH:28]([CH2:30][C:24]([OH:32])([CH2:25]3)[CH2:23]1)[CH2:29]2)=[O:21]>>[CH3:18][O:19][C:20]([C:22]12[CH2:31][CH:26]3[CH2:27][CH:28]([CH2:30][C:24]([O:32][C:1](=[O:4])[CH:2]=[CH2:3])([CH2:25]3)[CH2:23]1)[CH2:29]2)=[O:21]

Participants

3

Reactant 2

HCID 144304Methyl 3-hydroxyadamantane-1-carboxylateHCID 219967831-Hydroxy-3-(acryloyloxymethyl)adamantane

Product 1

HCID 219967781-Methoxycarbonyl-3-acryloyloxyadamantaneYield 87%

Procedure

The reaction was conducted in the same manner as the step of Example 36 (2) except that 1-methoxycarbonyl-3-hydroxyadamantane was used instead of the 1,3-dicarboxy-5-adamantanol, and, as a result, a 1-methoxycarbonyl-3-acryloyloxyadamantane (yield: 87%, white solid) was obtained.

Sources & evidence

ORD record
ord-c9786bc93c7743adb0418a5c12b41e1d
Source dataset
uspto-grants-2001_05
Patent number
US06235851B1

Reaction notes

Loading…