HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21993863, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Tert-butoxycarbonyl-1'-(3-phenylpropan-1-yl)-4,4'-bipiperidine | HCID 21993945 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 21993863 | HCID 21993863 | — |
Reaction Steps
In 20 ml of methanol was dissolved 3.425 g (8.860 mM) of 1-tert-butoxycarbonyl-1′-(3-phenylpropan-1-yl)-4,4′-bipiperidine, followed by addition of 5 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 6 hours. This reaction mixture was concentrated and crystallized from methanol-diethyl ether to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235731B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-c8733284518649afb86205a9ecedf7fb |
| Source note | uspto-grants-2001_05 |