4-Aminocyclohexanecarboxylic acid → Methyl 4-aminocyclohexane-1-carboxylate--hydrogen chloride (1/1)

Participants

Reaction Steps

To 5.109 g (35.680 mM) of 4-aminocyclohexane-carboxylic acid was added 50 ml of 10% HCl/methanol and the mixture was refluxed overnight. The solvent was then distilled off under reduced pressure and the residue was crystallized from methanol-diethyl ether to provide the title compound.

Provenance & Evidence