HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-4-(aminomethyl)piperidine → HCID 21993912, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-4-(aminomethyl)piperidine | HCID 736817 | — |
| Reactant | HCID 12549382 | HCID 12549382 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 21993912 | HCID 21993912 | — |
Reaction Steps
A solution of 2.405 g (5.947 mM) of phenyl di-phenoxyphosphorylmethanesulfonate and 1.66 g (7.73 mM) of 1-(tert-butoxycarbonyl)piperidine-4-ylmethylamine in 50 ml of toluene was refluxed overnight. The solvent was then distilled off under reduced pressure and the residue was purified by silica gel column chromatography (hexane-ethyl acetate:2/1 to 1/1) to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235731B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-15d5e5acccdf4c16a3dff16c1b7a01cd |
| Source note | uspto-grants-2001_05 |