Hydrochloric Acid → HCID 10943925, compound

HRID 1978404Notes

Reaction equation

HRID 1978404 reaction equation
[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([C:13]([O:15]CC)=[O:14])=[CH:4]2.[OH-].[Na+].Cl>C(O)C>[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([C:13]([OH:15])=[O:14])=[CH:4]2

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 12038723HCID 12038723, compound

Product 1

HCID 10943925HCID 10943925, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 64.047 g (260.0 mM) of ethyl 5-thia-1,8b-diazaacenaphthylene-4-carboxylate in 400 ml of ethanol was added 156 ml (312 mM) of 2N-aqueous solution of sodium hydroxide and the mixture was stirred at room temperature for one hour. To this reaction mixture was added concentrated hydrochloric acid with stirring to bring pH into the range of 4-5 and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

Workup

  1. stirringwith stirring
  2. filtrationthe resulting precipitate was recovered by filtration
  3. washrinsed serially with ethanol and diethyl ether

Sources & evidence

ORD record
ord-2dc2c4ae207a4de4b816a04c9c583a66
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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