反应详情

To a solution of 64.047 g (260.0 mM) of ethyl 5-thia-1,8b-diazaacenaphthylene-4-carboxylate in 400 ml of ethanol was added 156 ml (312 mM) of 2N-aqueous solution of sodium hydroxide and the mixture was stirred at room temperature for one hour. To this reaction mixture was added concentrated hydrochloric acid with stirring to bring pH into the range of 4-5 and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

1. stirringwith stirring
2. filtrationthe resulting precipitate was recovered by filtration
3. washrinsed serially with ethanol and diethyl ether