Hydrochloride methanol → HCID 21994030, compound

HRID 1978446Notes

Reaction equation

HRID 1978446 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([C:17]2[S:27][C:26]3[N:28]4[C:19](=[CH:20][N:21]=[C:22]4[CH:23]=[CH:24][CH:25]=3)[CH:18]=2)=[O:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:29].[CH3:30]O>C(O)C>[ClH:29].[ClH:29].[CH3:30][N:10]([CH2:11][CH2:12][CH2:13][NH:14][C:15]([C:17]1[S:27][C:26]2[N:28]3[C:19](=[CH:20][N:21]=[C:22]3[CH:23]=[CH:24][CH:25]=2)[CH:18]=1)=[O:16])[CH2:9][CH2:8][CH2:7][C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 21893726Hydrochloride methanolHCID 21994128HCID 21994128, compound

Product 1

HCID 21994030HCID 21994030, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 577.3 mg (1.42 mM) of N-[3-(N-(3-phenylpropan-1-yl)amino)propan-1-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol (6 ml) was added 2.0 ml (8.0 mM) of 4N-HCl/methanol at room temperature and the mixture was stirred for several minutes. The solvent was then distilled off under reduced pressure to provide the title compound.

Workup

  1. distillationThe solvent was then distilled off under reduced pressure

Sources & evidence

ORD record
ord-7693372c8747493dadacf451f5d74cab
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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