Hydrochloric Acid → n-[1-(4-Phenylbutan-1-yl)piperidin-4-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide dihydrochloride

Participants

Reaction Steps

To a solution of 437.4 mg (1.01 mM) of N-[1-(4-phenylbutan-1-yl)piperidin-4-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol (10 ml) was added 0.5 ml (6 mM) of 12N-hydrochloric acid and the mixture was stirred at room temperature for 16 hours. After this reaction mixture was concentrated, a small amount of ethanol was added to the residue and the crystals were collected by filtration and rinsed with ethanol and diethyl ether to provide the title compound as orange-colored crystals.

Provenance & Evidence