Hydrochloric Acid → HCID 21993720, compound

Participants

Reaction Steps

To a solution of 1.59 g (3.31 mM) of N-[4-(4-phenylpiperidin-1-ylmethyl)benzyl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol was added 1 ml (12 mM) of 12N-hydrochloric acid at room temperature, and the mixture was stirred for several minutes. This reaction mixture was concentrated and, after addition of ethanol and diethyl ether, the crystal crop was harvested by filtration and rinsed with ethanol and diethyl ether to provide the title compound as orange-colored crystals.

Provenance & Evidence